---
title: G. Methylation
author: Martin Morgan (mtmorgan@fredhutch.org)
date: "`r Sys.Date()`"
output:
  BiocStyle::html_document:
    toc: true
vignette: >
  %\VignetteIndexEntry{G. Methylation}
  %\VignetteEngine{knitr::rmarkdown}
  \usepackage[utf8]{inputenc}
---

```{r style, echo=FALSE, results='asis'}
BiocStyle::markdown()
```

# Motivation

# Work flow & statistical issues

## Methylation microarrays and differentially methylated probesets

## Differential methylated regions

Hunting bumps

Testing significance

# Practical: [minfi](http://bioconductor.org/packages/devel/bioc/html/minfi.html)

