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The p-values of the global\nlikelihood ratio test (E2) are obtained using the excat\ndistribution and permutation. The other four test statistics\nare obtained using permutation . 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'Selected'\ngenes are those present at the top of the list in various\nranking methods (currently 14). In addition, the stability of\nthe findings can be taken into account in the final ranking by\nexamining perturbed versions of the original data set, e.g. by\nleaving samples, swapping class labels, generating bootstrap\nreplicates or adding noise. 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